What is DBS?
DBS — Deep Brain Stimulation — is a surgically implanted device that delivers continuous electrical stimulation to specific brain targets through implanted electrodes. It modulates abnormal neural circuits responsible for motor symptoms in Parkinson's disease (PD), tremor, and dystonia, or for behavioral symptoms in OCD and depression.
Dr. Sun Chenyan was the first in China to implement DBS for Parkinson's disease. At Eber Medical Group, DBS is performed in a Siemens Hybrid Operating Room with real-time intraoperative neurophysiological monitoring (IONM), stereotactic navigation, and microelectrode recording (MER) for precise electrode placement.
Conditions Treated with DBS
| Condition | Brain Target | Expected Benefit |
|---|---|---|
| Parkinson's Disease | STN or GPi | 50–70% reduction in motor fluctuations, tremor, rigidity |
| Essential Tremor | VIM (thalamus) | 70–90% tremor reduction; immediate effect |
| Dystonia (primary/secondary) | GPi | Significant posture and movement improvement over weeks–months |
| OCD (refractory) | VC/VS or STN | 30–50% Y-BOCS score improvement |
| Treatment-Resistant Depression | SCC (Cg25) | Mood normalization in select patients |
| Epilepsy (refractory) | ANT (thalamus) | Seizure frequency reduction 40–60% |
DBS Procedure Steps at Eber Medical Group
- Preoperative Evaluation (3–5 days): Neurological exam, levodopa challenge (for PD), MRI/CT stereotactic planning, neuropsychological testing
- Lead Implantation Surgery: Stereotactic frame placement, target coordinates calculated, burr holes, microelectrode recording (MER) for physiological target confirmation
- Siemens Hybrid OR: Real-time fluoroscopic or intraoperative MRI guidance confirms electrode position during surgery
- IPG Implantation: Impulse generator (Medtronic, Abbott, or Boston Scientific) implanted subcutaneously in chest or abdomen; connected to DBS leads via subcutaneous extension
- Programming: Device activation 1–2 weeks post-surgery; optimization over 3–6 months outpatient visits
DBS + TCM Integration at Eber
Uniquely at Eber, DBS is combined with Traditional Chinese Medicine (TCM) — particularly acupuncture and herbal medicine — to address non-motor symptoms of Parkinson's disease that DBS alone does not target: sleep disorders, constipation, depression, freezing of gait, and cognitive changes. This integrated Western medicine + TCM multidisciplinary approach provides more comprehensive symptom management than DBS alone.